<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2019-1-66-71</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1048</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Management of patients with acute back pain now and 10 years ago</article-title><trans-title-group xml:lang="ru"><trans-title>Ведение пациентов с острой болью в спине в настоящее время и 10 лет назад</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Парфенов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Parfenov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Анатольевич Парфенов</p><p>Кафедра нервных болезней и нейрохирургии лечебного факультета </p><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Vladimir Anatolyevich Parfenov</p><p>Department of Nervous System Diseases and Neurosurgery, Faculty of General Medicine</p><p>11, Rossolimo St., Build. 1, Moscow 119021</p><p> </p></bio><email xlink:type="simple">vladimirparfenov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калимеева</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalimeeva</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней и нейрохирургии лечебного факультета</p><p> </p></bio><bio xml:lang="en"><p>Department of Nervous System Diseases and Neurosurgery, Faculty of General Medicine</p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Герасимова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gerasimova</surname><given-names>О. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>129329, Москва, ул. Кольская, 2</p><p> </p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский университет)» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Поликлиника №6 ЗАО «Медицинские услуги»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>ZAO “Meditsinskie Uslugi” (Medical Services), Polyclinic Six</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>05</day><month>03</month><year>2019</year></pub-date><volume>11</volume><issue>1</issue><fpage>66</fpage><lpage>71</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Parfenov V.A., Kalimeeva E.Y., Gerasimova О.N., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Парфенов В.А., Калимеева Е.Ю., Герасимова О.Н.</copyright-holder><copyright-holder xml:lang="en">Parfenov V.A., Kalimeeva E.Y., Gerasimova О.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1048">https://nnp.ima-press.net/nnp/article/view/1048</self-uri><abstract><p>Management of patients with acute back pain is one of the urgent problems in modern medicine.</p><sec><title>Objective</title><p>Objective: to assess the management of patients with acute and subacute back pain in 2007–2008 and 2017–2018.</p></sec><sec><title>Patients and methods</title><p>Patients and methods. The authors present their own experience in treating 140 patients (87 women and 53 men) (mean age, 50.7±17.6 years) at present and 70 patients (40 women and 30 men) (mean age, 46.5±15.0 years) 10 years ago.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. The experience shows the high efficiency of managing patients with acute back pain during information sharing (an educational conversation), a personalized approach (treatment of concomitant diseases and conditions) and, use of nonsteroidal anti-inflammatory drugs. However, these methods are not widely used in general clinical practice now, as 10 years ago.</p></sec><sec><title>Conclusion</title><p>Conclusion. To improve the quality of medical care, the additional education and training of physicians are required for the management of patients with back pain.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Цель исследования – оценка ведения пациентов с острой и подострой болью в спине в 2007–2008 и 2017–2018 гг.</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Представлен собственный опыт лечения 140 пациентов (средний возраст 50,7±17,6 года, 87 женщин и 53 мужчины) в настоящее время и 70 пациентов (средний возраст 46,5±15,0 лет, 40 женщин и 30 мужчин) 10 лет назад.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Наш опыт показывает высокую эффективность ведения пациентов с острой болью в спине на фоне информирования (образовательной беседы), персонализированного подхода (лечение сочетанных заболеваний и состояний) и применения нестероидных противовоспалительных препаратов. Однако эти методы в настоящее время, как и 10 лет назад, не получили широкого распространения в общей клинической практике.</p></sec><sec><title>Заключение</title><p>Заключение. Для улучшения качества оказания медицинской помощи необходимы дополнительное образование и повышение квалификации врачей в области ведения пациентов с болью в спине.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>острая дорсалгия</kwd><kwd>подострая дорсалгия</kwd><kwd>дискогенная радикулопатия</kwd><kwd>школа при боли в спине</kwd><kwd>нестероидные противовоспалительные препараты</kwd><kwd>мелоксикам</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute dorsalgia</kwd><kwd>subacute dorsalgia</kwd><kwd>discogenic radiculopathy</kwd><kwd>back pain school</kwd><kwd>nonsteroidal anti-inflammatory drugs</kwd><kwd>meloxicam</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Aug 22;386(9995): 743-800. doi: 10.1016/S0140-6736(15)60692-4. Epub 2015 Jun 7.</mixed-citation><mixed-citation xml:lang="en">Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Aug 22;386(9995): 743-800. doi: 10.1016/S0140-6736(15)60692-4. Epub 2015 Jun 7.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Яхно НН, Кукушкин МЛ, Чурюканов МВ, Сыровегин АВ. Результаты открытого мультицентрового исследования «МЕРИДИАН» по оценке распространенности болевых синдромов в амбулаторной практике и терапевтических предпочтений врачей. Российский журнал боли. 2012;(3):10-4.</mixed-citation><mixed-citation xml:lang="en">Yakhno NN, Kukushkin ML, Churyukanov MV, Syrovegin AV. The results of the open multicenter study MERIDIAN to assess the prevalence of pain syndromes in outpatient practice and therapeutic preferences of doctors. Rossiiskii zhurnal boli. 2012;(3):10-4. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Koes BW, van Tulder M, Lin CW, et al. An updated overview of clinical guidelines for the management of non-specific low back pain in primary care. Eur Spine J. 2010 Dec;19(12): 2075-94. doi: 10.1007/s00586-010-1502-y. Epub 2010 Jul 3.</mixed-citation><mixed-citation xml:lang="en">Koes BW, van Tulder M, Lin CW, et al. An updated overview of clinical guidelines for the management of non-specific low back pain in primary care. Eur Spine J. 2010 Dec;19(12): 2075-94. doi: 10.1007/s00586-010-1502-y. Epub 2010 Jul 3.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Qaseem A, Wilt TJ, McLean RM, Forciea MA. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2017; 166 (7):514-530.</mixed-citation><mixed-citation xml:lang="en">Qaseem A, Wilt TJ, McLean RM, Forciea MA. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2017; 166 (7):514-530.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Wong J, Cote P, Sutton DA, et al. Clinical practice guidelines for the noninvasive management of low back pain: A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. Eur J Pain. 2017 Feb;21(2):201-216. doi: 10.1002/ejp.931. Epub 2016 Oct 6.</mixed-citation><mixed-citation xml:lang="en">Wong J, Cote P, Sutton DA, et al. Clinical practice guidelines for the noninvasive management of low back pain: A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. Eur J Pain. 2017 Feb;21(2):201-216. doi: 10.1002/ejp.931. Epub 2016 Oct 6.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Low Back Pain and Sciatica in Over 16s: Assessment and Management. Clinical Guidelines. London: National Institute for Health and Care Excellence (UK); 2016. www.nice.org.uk/guidance/ng5</mixed-citation><mixed-citation xml:lang="en">Low Back Pain and Sciatica in Over 16s: Assessment and Management. Clinical Guidelines. London: National Institute for Health and Care Excellence (UK); 2016. www.nice.org.uk/guidance/ng5</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Stochkendahl MJ, Kjaer P, Hartvigsen J, et al. National Clinical Guidelines for non-surgical treatment of patients with recent onset low back pain or lumbar radiculopathy. Eur Spine J. 2018 Jan;27(1):60-75. doi: 10.1007/s00586-017-5099-2. Epub 2017 Apr 20.</mixed-citation><mixed-citation xml:lang="en">Stochkendahl MJ, Kjaer P, Hartvigsen J, et al. National Clinical Guidelines for non-surgical treatment of patients with recent onset low back pain or lumbar radiculopathy. Eur Spine J. 2018 Jan;27(1):60-75. doi: 10.1007/s00586-017-5099-2. Epub 2017 Apr 20.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen SP, Hooten WM. Advances in the diagnosis and management of neck pain. BMJ. 2017 Aug 14;358:j3221. doi: 10.1136/bmj.j3221</mixed-citation><mixed-citation xml:lang="en">Cohen SP, Hooten WM. Advances in the diagnosis and management of neck pain. BMJ. 2017 Aug 14;358:j3221. doi: 10.1136/bmj.j3221</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Герасимова ОН, Парфенов ВА. Лечение острой неспецифической боли в спине в амбулаторной практике. Неврология, нейропсихиатрия, психосоматика. 2009;1(3-4): 40-6.</mixed-citation><mixed-citation xml:lang="en">Gerasimova ON, Parfenov VA. Treatment for acute nonspecific back pain in outpatient practice. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2009;1(3-4): 40-6. (In Russ.). doi: 10.14412/2074-2711-2009-54</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Герасимова ОН, Парфенов ВА, Калимеева ЕЮ. Лечение пациентов с острой и подострой дорсалгией. Неврология, нейропсихиатрия, психосоматика. 2018;10(3):36–41. doi: 10.14412/2074-2711-2018-3-36-41</mixed-citation><mixed-citation xml:lang="en">Gerasimova ON, Parfenov VA, Kalimeeva EYu. Treatment of patients with acute and subacute dorsalgia. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, neuropsychiatry, psychosomatics. 2018;10(3):36–41. (In Russ.). doi: 10.14412/2074-2711-2018-3-36-41</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Henschke N, Maher CG, Refshauge KM, et al. Prognosis in patients with recent onset low back pain in Australian primary care: inception cohort study. BMJ. 2008 Jul 7;337:a171. doi: 10.1136/bmj.a171.</mixed-citation><mixed-citation xml:lang="en">Henschke N, Maher CG, Refshauge KM, et al. Prognosis in patients with recent onset low back pain in Australian primary care: inception cohort study. BMJ. 2008 Jul 7;337:a171. doi: 10.1136/bmj.a171.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Калимеева ЕЮ, Парфенов ВА. Оптимизация ведения пациентов с неспецифической болью в нижней части спины. Медицинский совет. 2016;9: 19-22.</mixed-citation><mixed-citation xml:lang="en">Kalimeeva EY, Parfenov VA. Optimizing management of patients with low back pain. Medical Council. 2016;9:19-22. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Rainville J, Smeets RJ, Bendix T, et al. Fear-avoidance beliefs and pain avoidance in low back pain – translating research into clinical practice. Spine J. 2011 Sep;11(9):895-903. doi: 10.1016/j.spinee.2011.08.006. Epub 2011 Sep 9.</mixed-citation><mixed-citation xml:lang="en">Rainville J, Smeets RJ, Bendix T, et al. Fear-avoidance beliefs and pain avoidance in low back pain – translating research into clinical practice. Spine J. 2011 Sep;11(9):895-903. doi: 10.1016/j.spinee.2011.08.006. Epub 2011 Sep 9.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Urquhar DM, Bell RJ, Cicuttini FM, et al. Negative beliefs about low back pain are associated with high pain intensity and high level disability in community-based women. BMC Musculoskelet Disord. 2008;9:148. doi: 10.1186/1471-2474-9-148</mixed-citation><mixed-citation xml:lang="en">Urquhar DM, Bell RJ, Cicuttini FM, et al. Negative beliefs about low back pain are associated with high pain intensity and high level disability in community-based women. BMC Musculoskelet Disord. 2008;9:148. doi: 10.1186/1471-2474-9-148</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Черепанов ЕА, Гладков АВ. Распространенность заблуждений о болях в спине в медицинской среде. Травматология и ортопедия России. 2012;3(65):111–117. doi: 10.21823/2311-2905-2012-3-111-117</mixed-citation><mixed-citation xml:lang="en">Cherepanov EA, Gladkov AV. Distribution of Misbeliefs about back pain among medical staff. Travmatologiya i ortopediya Rossii = Traumatology and Orthopedics of Russia. 2012; 3(65):111–117. (In Russ.). doi: 10.21823/2311-2905-2012-3-111-117</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Poquet N, Lin CW, Heymans MW, et al. Back schools for acute and subacute non-specific low-back pain. Cochrane Database Syst Rev. 2016 Apr 26;4:CD008325. doi: 10.1002/14651858.CD008325.pub2.</mixed-citation><mixed-citation xml:lang="en">Poquet N, Lin CW, Heymans MW, et al. Back schools for acute and subacute non-specific low-back pain. Cochrane Database Syst Rev. 2016 Apr 26;4:CD008325. doi: 10.1002/14651858.CD008325.pub2.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Van Hooff ML, Ter Avest W, Horsting PP, et al. A short, intensive cognitivebehavioral pain management program reduces health-care use in patients withchronic low back pain: two-year follow-up results of a prospective cohort. Eur Spine J. 2012 Jul;21(7):1257-64. doi: http://dx.doi.org/10.1007/s00586-011-2091-0.</mixed-citation><mixed-citation xml:lang="en">Van Hooff ML, Ter Avest W, Horsting PP, et al. A short, intensive cognitivebehavioral pain management program reduces health-care use in patients withchronic low back pain: two-year follow-up results of a prospective cohort. Eur Spine J. 2012 Jul;21(7):1257-64. doi: http://dx.doi.org/10.1007/s00586-011-2091-0.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ojha HA, Wyrsta NJ, Davenport TE, et al. Timing of Physical Therapy Initiation for Nonsurgical Management of Musculoskeletal Disorders and Effects on Patient Outcomes: A Systematic Review. J Orthop Sports Phys Ther. 2016 Feb;46(2):56-70. doi: 10.2519/jospt.2016.6138. Epub 2016 Jan 11.</mixed-citation><mixed-citation xml:lang="en">Ojha HA, Wyrsta NJ, Davenport TE, et al. Timing of Physical Therapy Initiation for Nonsurgical Management of Musculoskeletal Disorders and Effects on Patient Outcomes: A Systematic Review. J Orthop Sports Phys Ther. 2016 Feb;46(2):56-70. doi: 10.2519/jospt.2016.6138. Epub 2016 Jan 11.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Vanti C, Andreatta S, Borghi S, et al. The effectiveness of walking versus exercise on pain and function in chronic low back pain: a systematic review and meta-analysis of randomized trials. Disabil Rehabil. 2017 Dec 5:1-11. doi: 10.1080/09638288.2017.1410730. [Epub ahead of print].</mixed-citation><mixed-citation xml:lang="en">Vanti C, Andreatta S, Borghi S, et al. The effectiveness of walking versus exercise on pain and function in chronic low back pain: a systematic review and meta-analysis of randomized trials. Disabil Rehabil. 2017 Dec 5:1-11. doi: 10.1080/09638288.2017.1410730. [Epub ahead of print].</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Hincapie CA, Cassidy JD, Cote P, et al. Chiropractic spinal manipulation and the risk for acute lumbar disc herniation: a belief elicitation study. Eur Spine J. 2018 Jul;27(7):1517-25. doi: 10.1007/s00586-017-5295-0. Epub 2017 Sep 18.</mixed-citation><mixed-citation xml:lang="en">Hincapie CA, Cassidy JD, Cote P, et al. Chiropractic spinal manipulation and the risk for acute lumbar disc herniation: a belief elicitation study. Eur Spine J. 2018 Jul;27(7):1517-25. doi: 10.1007/s00586-017-5295-0. Epub 2017 Sep 18.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Ferrell B, Argoff CE, Epplin J, et al. Pharmacological management of persistent pain in older persons. American geriatrics society panel on the pharmacological management of persistent pain in older persons. J Am Geriatr Soc. 2009;57(8):1331-146. doi: 10.1111/j.1526-4637.2009.00699.x.</mixed-citation><mixed-citation xml:lang="en">Ferrell B, Argoff CE, Epplin J, et al. Pharmacological management of persistent pain in older persons. American geriatrics society panel on the pharmacological management of persistent pain in older persons. J Am Geriatr Soc. 2009;57(8):1331-146. doi: 10.1111/j.1526-4637.2009.00699.x.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ, Яхно НН, Каратеев АЕ и др. Общие принципы лечения скелетномышечной боли: междисциплинарный консенсус. Научно-практическая ревматология. 2016;54(3):247-65. doi: 10.14412/1995-4484-2016-247-265</mixed-citation><mixed-citation xml:lang="en">Nasonov EL, Yakhno NN, Karateev AE, et al. General principles of treatment for musculoskeletal pain: interdisciplinary consensus. Nauchno-prakticheskaya revmatologiya = Rheumatology Science and Practice. 2016;54(3):247-65. (In Russ.). doi: 10.14412/1995-4484-2016-247-265</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Hawkey C, Kahan A, Steinbrü ck K, et al. Gastrointestinal tolerability of meloxicam compared to diclofenac in osteoarthritis patients. International MELISSA Study Group. Meloxicam Large-scale International Study SafetyAssessment. Br J Rheumatol. 1998 Sep;37(9):937-45.</mixed-citation><mixed-citation xml:lang="en">Hawkey C, Kahan A, Steinbrü ck K, et al. Gastrointestinal tolerability of meloxicam compared to diclofenac in osteoarthritis patients. International MELISSA Study Group. Meloxicam Large-scale International Study SafetyAssessment. Br J Rheumatol. 1998 Sep;37(9):937-45.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Singh G, Lanes S, Triadafilopoulos S. Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicam. Am J Med. 2004 Jul 15; 117(2):100-6.</mixed-citation><mixed-citation xml:lang="en">Singh G, Lanes S, Triadafilopoulos S. Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicam. Am J Med. 2004 Jul 15; 117(2):100-6.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Chen YF, Jobanputra P, Barton P, et al. Cyclooxygenase-2 selective non-steroidal antiinflammatory (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis or rheumatoid arthritis: a systematic review and economic evaluation. Health Technology Assessment. 2008;12(11): 1–178. doi: 10.3310/hta12110. http://www.hta.ac.uk/project/1383.asp.</mixed-citation><mixed-citation xml:lang="en">Chen YF, Jobanputra P, Barton P, et al. Cyclooxygenase-2 selective non-steroidal antiinflammatory (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis or rheumatoid arthritis: a systematic review and economic evaluation. Health Technology Assessment. 2008;12(11): 1–178. doi: 10.3310/hta12110. http://www.hta.ac.uk/project/1383.asp.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
