nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2018-4-123-128nnp-1007Research ArticleREVIEWSОБЗОРЫTherapy for acute nonspecific back pain: new additional opportunitiesТерапия острой неспецифической боли в спине: новые возможностиГоловачеваВ. А.GolovachevaV. A.

Вероника Александровна Головачева - кафедра нервных болезней и нейрохирургии лечебного факультета.

119021, Москва, ул. Россолимо, 11, стр. 1

Veronika Aleksandrovna Golovacheva - Department of Nervous System Diseases and Neurosurgery, Faculty of General Medicine.

11, Rossolimo St., Build. 1, Moscow 119021

xoxo.veronicka@gmail.comГоловачеваА. А.GolovachevaA. A.

Кафедра нервных болезней и нейрохирургии лечебного факультета.

119021, Москва, ул. Россолимо, 11, стр. 1

Department of Nervous System Diseases and Neurosurgery, Faculty of General Medicine.

11, Rossolimo St., Build. 1, Moscow 119021

ФГАОУВО «Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский университет)» Минздрава РоссииРоссияI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaRussian Federation201815122018104123128Copyright © Golovacheva V.A., Golovacheva A.A., 20182018Головачева В.А., Головачева А.А.Golovacheva V.A., Golovacheva A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1007

Information about a favorable prognosis for a patient, recommendations for activities, and optimal pharmacotherapy are a mainstay in the effective treatment of acute nonspecific low back pain (NLBP). Standard pharmacotherapy for acute NLBP includes nonsteroidal anti-inflammatory drugs (NSAIDs). However, the longer their administration and larger doses, the higher the risk of side effects are. NSAIDs are contraindicated in some cases. In this connection, it has become necessary to search for new opportunities for the pharmacotherapy of acute NLBP. The results of experimental studies have demonstrated the analgesic and anti-inflammatory effects of high-dose B vitamins. Clinical trials have confirmed the efficacy of vitamin B complex (thiamine, pyridoxine, and cyanocobalamin) in the treatment of acute NLBP. The paper considers the practical significance of concomitant administration of B vitamins and NSAIDs in NLBP and notes the efficacy of milgamma used both alone and in combination with NSAIDs in the treatment of acute NLBP.

Информирование пациента о благоприятном прогнозе, рекомендация сохранять активность и оптимальная фармакотерапия — основа эффективного лечения острой поясничной неспецифической боли (ПНБ). К стандартной фармакотерапии острой ПНБ относятся нестероидные противовоспалительные препараты (НПВП). Однако чем длительнее их прием и больше дозы, тем выше риск развития побочных эффектов. В ряде случаев есть противопоказания к назначению НПВП. В связи с этим возникла необходимость поиска новых возможностей фармакотерапии острой ПНБ. Результаты экспериментальных исследований продемонстрировали противоболевой и противовоспалительный эффект витаминов группы В в высоких дозах. В клинических исследованиях получены данные, подтверждающие эффективность комплекса витаминов группы В (тиамин, пиридоксин, цианкоба-ламин) в лечении острой ПНБ. Рассматривается практическая значимость комбинированного применения витаминов группы В и НПВП при ПНБ. Отмечается эффективность Мильгаммы® в лечении острой ПНБ как в сочетании с НПВП, так и в качестве монотерапии.

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The authors declare that there are no conflicts of interest present.