nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2009-24nnp-10Research ArticleCLINICAL OBSERVATIONSКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCONCOMITANCE OF INFANTILE AUTISM AND EPILEPSY: ETIOPATHOGENIC ASPECTSСочетание детского аутизма и эпилепсии: патогенетические аспектыМалининаЕ. В.MalininaE. V.

Челябинск

Chelyabinsk

malinina.e@rambler.ruСупрунС. А.SuprunS. A.

Челябинск

Chelyabinsk

info@ima-press.netМарковаЕ. А.MarkovaE. A.

Челябинск

Chelyabinsk

info@ima-press.netГОУ ДПО «Уральская государственная медицинская академия дополнительного образования Росздрава»РоссияUrals State Medical Academy of Postgraduate Education, Russian Agency of Health CareRussian Federation200911032009115153Copyright © Malinina E.V., Suprun S.A., Markova E.A., 20092009Малинина Е.В., Супрун С.А., Маркова Е.А.Malinina E.V., Suprun S.A., Markova E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/10

The pathogenetic aspects of a concomitance of infantile autism and epilepsy are considered. Data on the implication of genetic and organic disorders and epileptiform activity in the origin of these disorders are given. A case of congenital malformation (schizencephalia) with the symptomatic partial seizures occurring in the presence of autistic disorder is described.

The pathogenetic aspects of a concomitance of infantile autism and epilepsy are considered. Data on the implication of genetic and organic disorders and epileptiform activity in the origin of these disorders are given. A case of congenital malformation (schizencephalia) with the symptomatic partial seizures occurring in the presence of autistic disorder is described.

infantile autismepilepsyinfantile autismepilepsyReferences<div><p>Психиатрия детского и подросткового возраста. Под ред. К. Гиллберга, Л. Хеллгрена. Рус. изд. под общ. ред. П.И. Сидорова; Пер. со швед. М.: ГОЭТАР-МЕД, 2004;544 с.</p><p>Rutter M. Genetic studies of autism: from the 1970s into the millennium. Journal of Abnormal Child Psychology 2000;28:3-14.</p><p>Fein D., Humes M., Kaplan E. et al. The origin of left-hemisphere dysfunction in autism. Psychological Bulletin 1984;95:258-81.</p><p>Fein D., Skoff B., Mirsky A.F. Clinical correlates of brainstem dysfunction in autistic children. Journal of Autism and Developmental Disorders 1981;11:303-16.</p><p>Bauman M., Kemper T.L. Histoanatomic observations of the brain in early infantile autism. Neurology 1985;35:866-74.</p><p>Courchesne E., Yeung-Courchesne R., Press G. et al. Hypoplasia of cerebellar vermal lobules VI and VII in autism. New England Journal of Medicine 1988;318:1349-54.</p><p>Piven J., Gayle J., Chase G. et al. A family history study of neuropsychiatric disorders in the adult siblings of autistic individuals. Journal of the American Academy of Child and Adolescent Psychiatry 1990;29.</p><p>Ремшмидт Х. Аутизм. Клинические проявления, причины и лечение: Пер. с нем. М.: Медицина, 2003;120 с.</p><p>Tsail L.Y. Psychopharmacology in Autism. Psychosom Med 1999;61:651-65.</p><p>Зенков Л.Р. Непароксизмальные эпилептические расстройства (руководство для врачей). М., 2006.</p><p>Зенков Л.Р. Фармакотерапия когнитивных нарушений детского возраста. Фарматека 2008;15:28-33.</p><p>Мухин К.Ю., Петрухин А.С., Глухова Л.Ю. Эпилепсия. Атлас электроклинической диагностики. М.: Альварес Паблишинг, 2004;440 с.</p><p>Berney T. P. Autism - an evolving concept. The British Journal of Psychiatry 2000;176:20-5.</p><p>Hurley Robin A., Lewine J.D., Jones G.M. et al. Application of Magnetoencephalography to the Study of Autism. J Neuropsychiatry Clin Neurosci 2000;12:1-3.</p><p>Kawasaki Y., Yokota K., Shinomiya M. et al. Electroencephalographic paroxysmal activities in the frontal area emerged in middle childhood and during adolescence in a follow-up study of autism. Journal of Autism and Developmental Disorders 1997;27:605-20.</p><p>Sobel D.F., Otsubo H., Smith M.C. Magnetoencephalography in Children with Landau-Kleffner Syndrome and Acquired Epileptic Aphasia. American Journal of Neuroradilogy 2000;21:301-7.</p><p>Алиханов А.А., Петрухин А.С. Нейровизуализация при эпилепсии: Пособие. М.: ЛЕНОМ, 2001;240 с.</p></div><br /><div><p>Психиатрия детского и подросткового возраста. Под ред. К. Гиллберга, Л. Хеллгрена. Рус. изд. под общ. ред. П.И. Сидорова; Пер. со швед. М.: ГОЭТАР-МЕД, 2004;544 с.</p><p>Rutter M. Genetic studies of autism: from the 1970s into the millennium. Journal of Abnormal Child Psychology 2000;28:3-14.</p><p>Fein D., Humes M., Kaplan E. et al. The origin of left-hemisphere dysfunction in autism. Psychological Bulletin 1984;95:258-81.</p><p>Fein D., Skoff B., Mirsky A.F. Clinical correlates of brainstem dysfunction in autistic children. Journal of Autism and Developmental Disorders 1981;11:303-16.</p><p>Bauman M., Kemper T.L. Histoanatomic observations of the brain in early infantile autism. Neurology 1985;35:866-74.</p><p>Courchesne E., Yeung-Courchesne R., Press G. et al. Hypoplasia of cerebellar vermal lobules VI and VII in autism. New England Journal of Medicine 1988;318:1349-54.</p><p>Piven J., Gayle J., Chase G. et al. A family history study of neuropsychiatric disorders in the adult siblings of autistic individuals. Journal of the American Academy of Child and Adolescent Psychiatry 1990;29.</p><p>Ремшмидт Х. Аутизм. Клинические проявления, причины и лечение: Пер. с нем. М.: Медицина, 2003;120 с.</p><p>Tsail L.Y. Psychopharmacology in Autism. Psychosom Med 1999;61:651-65.</p><p>Зенков Л.Р. Непароксизмальные эпилептические расстройства (руководство для врачей). М., 2006.</p><p>Зенков Л.Р. Фармакотерапия когнитивных нарушений детского возраста. Фарматека 2008;15:28-33.</p><p>Мухин К.Ю., Петрухин А.С., Глухова Л.Ю. Эпилепсия. Атлас электроклинической диагностики. М.: Альварес Паблишинг, 2004;440 с.</p><p>Berney T. P. Autism - an evolving concept. The British Journal of Psychiatry 2000;176:20-5.</p><p>Hurley Robin A., Lewine J.D., Jones G.M. et al. Application of Magnetoencephalography to the Study of Autism. J Neuropsychiatry Clin Neurosci 2000;12:1-3.</p><p>Kawasaki Y., Yokota K., Shinomiya M. et al. Electroencephalographic paroxysmal activities in the frontal area emerged in middle childhood and during adolescence in a follow-up study of autism. Journal of Autism and Developmental Disorders 1997;27:605-20.</p><p>Sobel D.F., Otsubo H., Smith M.C. Magnetoencephalography in Children with Landau-Kleffner Syndrome and Acquired Epileptic Aphasia. American Journal of Neuroradilogy 2000;21:301-7.</p><p>Алиханов А.А., Петрухин А.С. Нейровизуализация при эпилепсии: Пособие. М.: ЛЕНОМ, 2001;240 с.</p></div><br />

The authors declare that there are no conflicts of interest present.